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Chart of Typical MSM Dosage
1,000 mg tablets 3 tablets twice a day 1 oz gel Apply topically 3 times a day
MSM Dosage
The generally recommended dosage is 1,500 to 6,000 mg of MSM per day. This is based on two double-blind studies of MSM for osteoarthritis of the knee.
Some people achieve results in as little as a week, but most research indicates that MSM may take more time to reduce joint problems.
For example, the 2006 Kim study period extended for 12 weeks, starting with a dose of 2 grams a day then increasing over the next three days to 6 grams per day. In that study, pain was reduced by 25%, with the most dramatic change reported between week two and week four; pain continued to decrease all the way through week twelve, indicating that a longer study might have shown even further benefit.
MSM can be introduced to the joint in three ways, orally (liquid or pill), topically (a gel applied directly onto the joint), or by physician injection. Most experts recommend a mix of oral and topical application for best results. Injection should only be performed by qualified medical personnel.
Read more about the specific applications of MSM to treat osteoarthritis related joint pain.
Read more about treating sport & exercise related injuries & joint pain with MSM.